Our Mission
RNA sequencing (RNA-seq) allows for insights into gene expression at high resolution. However, bulk RNA-seq lacks the ability to examine cellular processes and expression patterns on an individual level resolution, which single cell RNA-seq (scRNA-seq) addresses. Despite its advantages, access to scRNA-seq remains limited by high cost, especially in low income settings.
We present Imperator, a web-based platform that aims to deconvolute bulk RNA-seq data into single-cell profiles without requiring user-generated scRNA-seq data. Imperator integrates tools like scSemiProfiler for deconvolution, scType for cell type annotation and Capybara for stem cell differentiation analysis. Designed for ease of use, the platform enables high-resolution analysis with minimal technical expertise to enhance accessibility to single-cell insights, offering a cost-effective and scalable solution. Furthermore, Imperator has the potential for major expansions that could see it branch out into many aspects of transcriptomic research.
With Imperator, we believe that access to cutting-edge transcriptomic insights shouldn't come with an extortionate price tag. Born from a vision to democratize single-cell RNA research, Imperator empowers scientists, clinicians, and students alike to explore the cellular intricacies of life without the financial or technical barriers that traditionally limit access. Our intuitive web-based platform harnesses the power of advanced tools like scSemiProfiler, scType, and Capybara to transform bulk RNA-seq data into detailed single-cell landscapes. There is now a reduced need for costly scRNA-seq datasets or specialised expertise, especially for those who do not have the necessary resources.
Imperator is more than a tool; it's a movement toward equitable, high-resolution biology for all.